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Exploratory efficacy criteria included scales for which no significant benefit was expected, but which were worth examining in preparation for the next clinical trial: on actimetry, the bradykinesia score (50th percentile: normal value = 18.6)

23 Pulmonary absorption gives instant presentation of levodopa to the absorptive membrane, which has a large surface area and low metabolic activity, 24 hence avoiding the variability in gastrointestinal absorption, poor pharmacokinetics, and consequent delayed on, or no on, or even dose failures with oral levodopa therapy

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Healthy B-12 levels support cell turnover and growth, which can lead to stronger nails, healthier hair, and more balanced skin over time