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CONTRAINDICATIONS History of serious hypersensitivity reaction to liraglutide or any of the excipients in Saxenda Pregnancy Personal or family history of medullary thyroid carcinoma (MTC) Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) PRECAUTIONS Kidney disease Saxenda has not been studied extensively in kidney disease
Key points In the kidney, pathways of selective autophagy form an integrated decision network that links sensing of cell stress and nutrients to lysosomal capacity and organelle-specific execution
Dtsch Arztebl Int , 111
In addition, as with any emerging pharmacology, careful and continued analysis for potential adverse effects is required, especially as these therapies advance for treatments in genetically diverse patient populations
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