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Estudos em modelos animais indicam que esses frmacos aumentam a fosforilao da via ERK1/2, um mecanismo crucial para a proteo neuronal
Lipolysis Enhancement and Lipogenesis Inhibition In obese Zucker rats, daily oral administration of AOD9604 significantly increased lipolytic activity in adipose tissue compared to controls, establishing direct adipocyte-level lipolysis stimulation as a key mechanism of action in pre-clinical models
PMID 27315480
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