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10.1038/cddis.2013.139 17 BrasierA
If central dopamine suppression is responsible, pro-dopaminergic agents like flibanserin or bremelanotide, both FDA-approved for hypoactive sexual desire disorder in premenopausal women, represent potential solutions
Selecting neutral or zwitterionic lipids, controlling the encapsulation temperature (often below the protein's denaturation point), and adding stabilizing excipients such as trehalose or sucrose can significantly enhance protein preservation
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