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When prescribing semaglutide to patients with autoimmune diseases, clinicians should implement a structured approach to patient selection, education, and monitoring

These predispositions do not determine outcome but may provide context for provider conversations about optimal dosing approach and expected response timeline

Available under the brand names Wegovy and Ozempic, Semaglutide is administered once weekly and has gained popularity for its effectiveness in helping patients achieve sustained weight loss

Lysosome-dependent cell death (LDCD), on the other hand, is mediated by lysosomal membrane permeabilization (LMP) under metabolic stress (223)