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Plant Pathol.DOI: 10.1111/mpp.12804 Gomez, G

Abstract Objectives To evaluate the effects of a very-low-calorie diet (VLCD) on insulin resistance (IR), metabolic gene expression, and fatty acid profiles in obese patients (body mass index [BMI] 30 kg/m 2 ) undergoing bariatric surgery compared to age- and sex-matched nonobese controls (BMI 25 kg/m 2 ) undergoing elective abdominal surgery

Why is this so crucial

In addition, these drugs must be discontinued in the face of a reduced estimated glomerular filtration rate, which limits their glucose-lowering effects substantially, and will be a typical risk in critically ill patients