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J Mol Neurosci 51:679686 Gilgun-Sherki Y, Melamed E, Offen D (2006) Anti-inflammatory drugs in the treatment of neurodegenerative diseases: current state

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Nevertheless, oxyntomodulin can be cleaved by DPP-4 in vitro (36, 56), and in animal studies, the anorectic effects of exogenous oxyntomodulin are increased after DPP-4 inhibition (56), while DPP-4-resistant oxyntomodulin analogs have been associated with improved glucose tolerance, reduced food intake, greater energy expenditure, and weight loss (57, 58)

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