Increased LPO and MDA levels have been reported in different conditions associated to OS, including physiological events, such as aging [38], and pathological conditions like schizophrenia [39], Alzheimers disease [40], inflammatory associated diseases [41], atherosclerosis [42] and chronic kidney disease [43]
These receptor complexes are found in several key locations throughout the body, including the brain, stomach, and kidney
GSH is a tripeptide antioxidant, in which its synthesis is catalyzed by GCS and GSH synthetase from glutamate, cysteine and glycine
doi:10.1074/jbc.M104516200 Fernandes RS, Cotter TG (1994) Apoptosis or necrosis: intracellular levels of glutathione influence mode of cell death