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Ipamorelin vs Sermorelin Ipamorelin vs Sermorelin Ipamorelin and Sermorelin both stimulate the GH axis, but they do so through different receptors

(2006) "Palmitoylation of Ligands, Receptors, and Intracellular Signaling Molecules"

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and for those tesamorelin-treated patients completing the 26-week treatment period that were re-randomized to tesamorelin (T-T group) or re-randomized to placebo, 36.6% and 32.0%, respectively, had impaired glucose tolerance, while 2.0% re-randomized to tesamorelin and 6.0% re-randomized to placebo had diet-controlled diabetes mellitus