Since the 2000s, incretin-based therapies for diabetes and obesity have become the focus of research and clinical practice
[1] Additionally, the label cautions that tirzepatide may reduce the exposure of oral contraceptives taken concomitantly, particularly after initiation and dose escalation, potentially requiring alternative contraceptive methods
GLP-1 agonists are medications that mimic or boost the effects of this natural hormone
Genes related to the Fenton reaction included those associated with the Warburg effect and proliferation, cytosolic iron-sulfur cluster synthesis, neutralization of HO, NADPH-dependent dehydrogenases, exogenous superoxide synthesis, cytosolic iron transporters, the proteasome, the oxidative-to-glycolytic shift, the Warburg effect, and central carbon metabolism in cancer obtained from KEGG database ( Other gene lists were custom-designed to capture broader biological processes and disease-relevant pathways