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In the STEP 2 trial, which evaluated patients with both obesity and type 2 diabetes, the average weight loss was 9.6%, highlighting that weight loss is often more challenging in patients with underlying insulin resistance
doi: 10.1185/03007995.2010.549466 166 HamiltonAPattersonSPorterDGaultVAHolscherC
In granulosa cells, p38 MAPK plays a role in generating pro-apoptotic signals (124)
Excess melanin causes hyperpigmentation issues
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