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J Clin Endocrinol Metab (2014) 99(7):245766
As the body adjusts to the medication, the intensity and frequency of nausea typically decrease
Proinflammatory cytokines further stimulate ROS overproduction aggravating ARDS and lung damage causing a vicious circle between oxidative stress and cytokine storm
This is the rationale for using vasodilator drugs such as phosphodiesterase (PDE) III inhibitors, papaverine, and pentoxifylline or micronutrients like magnesium (Mg 2+ ) which seem to have protective effects in the noise-exposed cochlea (Figure 2)
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