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The gastrointestinal tract and the brain are involved in a complex bidirectional communication, which is mediated by the endocrine, immune and neural pathways, involving a plethora of different neurotransmitters, cytokines and peptide hormones [98]

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Trulicity dosing information Usual Adult Trulicity Dose for Diabetes Type 2 Initial dose: Trulicity 0.75 mg subcutaneously once a week The dose may be increased to 1.5 from 0.75, then in 1.5 mg increments for additional glycemic control

Acta 1792 , 8392 (2009)