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It binds copper ions and delivers them to cells, activating copper-dependent enzymes involved in antioxidant defense, angiogenesis, and tissue remodeling
By neutralizing ROS that would otherwise damage lipids, proteins, DNA, and transcriptional regulation, melatonin normally limits oxidative injury
219 Ischaemia arguably upregulates some of these receptors, although astrocytic phagocytosis is tightly coordinated with microglial one
MEF, mouse embryonic fibroblasts
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