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For now, the findings provide early evidence that the fertility conversation surrounding GLP-1 medications may be more nuanced than previously thought.

3b,c), although, in both cases, the contribution from genetics was relatively modest compared with that from non-genetic factors (Supplementary Table 22)

This approach has already been implemented for various cancers, including colorectal (Sasaki and Clevers, 2018), gastric (Yan et al., 2018), liver (Yang et al., 2024) and even glioblastoma (Jacob et al., 2020)