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Bupropion/Naltrexone: This combination targets the brain's reward system to help curb food cravings and support weight management
The biggest difference between the two is the dosing schedule
Sleep fragments, which raises cortisol and appetite together
The SELECT trial showed cardiovascular benefit for semaglutide in a different population (obesity without diabetes), but whether semaglutide's modest advantage over dulaglutide in glycaemic control translates to a meaningful difference in hard endpoints for type-2 diabetes patients remains an open question
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