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introduced a new series of (R)-3-amino-1-((3aS,7aS)-octahydro-1H-indol-1-yl)-4-(2,4,5-trifluorophenyl) butan-1-one analogs as a novel class of DPP-4 inhibitors
Cysteine has -SH bonds that are at redox state are the main components in the glutathione molecule
Consistently, a decrease of O-GlcNAc induced by injecting a lentivirus expressing shRNA against O-GlcNAc transferase in dentate gyrus, impaired the production of DCX + neuroblasts and NeuN + neurons, while in vitro it promoted astrocyte differentiation
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