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According to the NIH, a symptom of vitamin B12 deficiency is weight loss [1]
Although cytotoxicity was not specific to homocysteine, endothelial cell detachment is also observed with cysteine (Dudman et al, 1991), an increase in the hydrogen peroxide-sensitive cellular fluorescent probe, 2,7-dichloro-fluorescein, was observed in cultured endothelial cells exposed to homocysteine (Toborek and Hennig, 1996)
Compounded versions are also widely available through licensed pharmacies, offering cost-effective access under physician supervision
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