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The JAK-STAT3 signaling pathway not only has a crucial role in the regulation of innate and adaptive immunity but in non-immune cells, it can control cell proliferation, metabolism, and cellular senescence in a context-dependent manner (see below)

Methods We used Mendelian randomization (MR) to investigate the association between genetically proxied GLP-1RA exposure and 12 psychiatric and neurodevelopmental conditions

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