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It typically presents as macrocytic megaloblastic anemia and neurological impairments, including sensory and motor disfunctions, predominantly in the lower extremities, ataxia, and in more advanced stages cognitive decline progressing to dementia, as well as psychiatric disturbances ( Subclinical B12 deficiency, however, is far more prevalent, affecting up to 26% of the general population
M.BoutronI.HoffmannT
peptide is hygroscopic Reconstitute in sterile water or appropriate buffered aqueous solution depending on assay requirements Avoid vigorous agitation during dissolution Filter sterilize if required (e.g
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