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For example, PERK and phosphorylated eIF2\u03b1 are prominently activated in the substantia nigra of PD patients, correlating with dopaminergic neuronal loss
While these represent uncontrolled single-person reports rather than systematic evidence, they align with the preclinical research findings
Despite their antigenic irrelevance, these cells not only are abundant within the TME but also frequently retain memory-associated properties and functional vigor [145,146,147]
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