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Many people begin noticing reduced appetite within the first few weeks of starting semaglutide, although weight loss typically becomes more noticeable after several weeks to a few months
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Transition phase (discontinuationwashoutstabilization): strictly implement clearance times based on drug characteristicsdiscontinue semaglutide for 2 months, tirzepatide for at least 1 month (161), and long-acting formulations like exenatide for at least 3 months (153, 158, 159, 162)
What matters is consistency, same day, every week, without skipping
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