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To assess its suitability as an oral therapeutic, we further investigated LLCs stability in physiological environments, its antioxidant performance under these conditions, and its gastrointestinal retention in vivo

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Apart from the well-documented GPx-like catalytic activity, ebselen is also reported for directly scavenging the biologically relevant ROS (like peroxyl and singlet oxygen) and reactive nitrogen species (peroxynitrite) with rate constants comparable to standard antioxidants

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