This suggests that GPR43 and GPR41 may not be part of the mechanism required for GLP-1 and PYY release from SCFAs
During our recent webinar with Second Opinion Media, Shaun Noorian explained an important challenge facing the peptide landscape today: the difference between products obtained from unregulated sources and medications produced within established pharmaceutical and compounding standards
For studies in DIO mice, male C57BL/6J mice were fed with a high-fat diet comprising 58% kilocalories from fat (D12331, Research Diets)
Additionally, some of the medications prescribed, including GLP-1s, bupropion, and topiramate, come with potential side effects such as nausea, dizziness, and metabolic disturbances, which may require close monitoring