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The higher proton leak may give a hint at mitochondrial adaptation to protect the cells from the formation of reactive oxygen species (ROS), potentially induced by a higher electron flux (49)

To validate these results, we treated GBM cells with C11-BODIPY (boron dipyrromethane difluoride), a fatty acid analog that emits red fluorescence that shifts to green fluorescence upon oxidation, and found that C5aR1 knockdown caused a shift from red to green fluorescence (Fig

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Well, as we become older, the glutathione levels start dwindling in the body, thereby accelerating the aging process