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Reported cases have occurred primarily in diabetic patients with significant renal insufficiency, including both intrinsic renal disease and renal hypoperfusion, often in the setting of multiple concomitant medical/surgical problems and multiple concomitant medications (see Recommendations for use in renal impairment under Dosage & Administration)
These preliminary findings remain of uncertain clinical relevance and do not suggest altered infection susceptibility
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(Prior studies have simply found a link between taking a GLP-1 receptor agonist and drinking lessbut didnt go so far as to actually prove that the medications caused people to drink less.) The new study, which was published in JAMA Psychiatry, could result in a future treatment for the more than 28 million American adults who struggle with alcohol-use disorder (AUD)
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