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Its release is stimulated by nutrient ingestion and neuroendocrine stimulation, eliciting several key metabolic responses, including enhanced insulin secretion, suppressed glucagon release, delayed gastric emptying, and increased satiety through both peripheral and central mechanisms [1]

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One example is a genetic variant near the gene OCA2 , in which the gene expression of OCA2 decreases in the presence of guanine, one of the building blocks of DNA

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