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8 Unveiling Off-Label Promotion, Utilization and Chronic Use Recent research suggests that off-label prescriptions for GLP-1 medications for patients without diabetes increased from 6% in 2018 to 27% in 2022, and have likely further increased throughout 2023 and 2024, given their growing popularity

A breakthrough in liver disease treatment A large global study has found that semaglutide, a medication best known for treating type 2 diabetes and obesity under the brand names Ozempic, Rybelsus, and Wegovy, may also be an effective treatment for a serious liver condition called MASH (metabolic dysfunction-associated steatohepatitis)

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Hepatocyte-derived GDF15 suppresses feeding and improves insulin sensitivity in obese mice