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The major catalase gene (katA) of Pseudomonas aeruginosa PA14 is under both positive and negative control of the global transactivator OxyR in response to hydrogen peroxide
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The mechanism involves modulation of prostaglandin and cytokine pathways
That could be because it's a needle, but it also may just be that for them, an injection signifies that their condition is more severe than they feel it is at that point
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