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The C2C12 mouse myoblast cell line was purchased from the Chinese Academy of Sciences/Stem Cell Bank (Shanghai, China)
Serious but Rare Side Effects In rare cases, metformin can cause a serious side effect called lactic acidosis, which requires immediate medical attention
doi:10.1542/peds.55.6.871
Weight changes , which some patients may experience as a secondary effect, generally become noticeable after 8 to 12 weeks of treatment, though this varies considerably between individuals
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