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La mayor prdida de peso se inform en un RCT de retatrutide (12 mg una vez por semana), un agonista triple dirigido a los receptores de GLP-1, GIP y glucagn que an no est aprobado por la FDA o disponible comercialmente

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By 2024, the associated weight loss was only half as large as the 2021 estimate, and the effect on A1C was not statistically different from zero

The most common side effects of Wegovy include: Nausea Vomiting Diarrhea Constipation Flatulence Stomach pain Headache Fatigue Upset stomach Dizziness Bloating Heartburn Runny nose Sore throat Consult a healthcare provider if side effects persist or worsen while on Wegovy