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Selenium supplementation of macrophages diminished the expression of lipopolysaccharide (LPS)-induced pro-inflammatory genes such as cyclooxygenase-2 (COX-2) and tumor necrosis factor- (TNF-) 59 , suggesting that selenium has anti-inflammatory effects on the immune system
An ex vivo experimental study showed a significant accumulation of MDA in the hearts of rats exposed to the TCDD, indicating that dioxin activates ferroptosis in the tissue (Mahdi et al
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