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GLP-1 can induce the expression of FNDC5 in pancreatic -cells through the interaction of its downstream transcription factor cAMP-response element binding protein (CREB) with binding elements in the FNDC5 promoter, thereby promoting the conversion of WAT to BAT and enhancing energy metabolism [85]
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Swim latency, swim distance, time spent in the target quadrant, and number of quadrant crossings were recorded using a computerized video tracking system [2]
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