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Clinical research The foundational characterization of GHK-Cu as a growth-modulating plasma tripeptide that functions by facilitating copper uptake into cells was published in Nature by Pickart et al
The peptide has to penetrate the outer skin barrier (stratum corneum), which limits how much active compound reaches the deeper dermal layers where collagen and elastin are produced
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A separate 12-week eye cream study in 41 women showed GHK-Cu outperforming both placebo and vitamin K cream for reducing lines and wrinkles around the eyes while increasing skin density
