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By Lana Pine | Published on June 19, 2025 4 min read People with diabetes who take glucagon-like peptide-1 (GLP-1) receptor agonists (such as Ozempic and Wegovy) may have more than twice the risk of developing a serious eye condition called neovascular age-related macular degeneration (nAMD) a leading cause of vision loss in older adults according to a large-scale study published in JAMA Ophthalmology

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In humans, calcitriol was shown to influence the activity of 3-hydroxysteroid dehydrogenase (3-HSD, an enzyme crucial for the production of progesterone and other steroid hormones) in granulosa cells, suggesting that vitamin D increases progesterone synthesis

Studies have shown that cytoplasmic virus recognition leads to the upregulation of glycolysis of macrophages through secondary interferon signal transduction