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Vegetarians and Vegans : Since vitamin B12 is primarily found in animal products, those following plant-based diets are at increased risk of deficiency
Athletes subject to anti-doping controls must exercise the greatest caution
For signicant deciencies, injections might be administered more frequently at the start (e.g., weekly), and once levels stabilize, the frequency can be reduced (e.g., monthly)
While increased permeability sounds beneficial, it can actually lead to irritation if the copper peptide concentration reaches deeper layers faster than intended
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