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The first significant factor in the pathogenesis of DN is glycemic variability and hyperglycemia

SWS, often called deep sleep, is suggested as one of the core stages within sleep architecture, broadly categorized into non-rapid eye movement (NREM) sleep and rapid eye movement (REM) sleep

(515) that administered probiotics as an adjunct to influenza vaccination evaluated outcomes using hemagglutination inhibition (HI) antibody assays

These platforms enable on-demand insulin or GLP-1 release triggered by elevated blood glucose levels, providing a closed-loop feedback mechanism that enhances therapeutic precision and reduces the risk of hypoglycemia [41]