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Zhang, B., Chen, Y., Bao, L

4-Hydroxynonenal 4-Hydroxynonenal (4HNE) is a lipoperoxidation-derived aldehyde that can damage proteins and DNA through the generation of covalent adducts and is implicated in the control of cell signaling 13,14

Oral semaglutide uses higher tablet doses to achieve bioavailability equivalent to lower injection doses, so both forms produce comparable weight loss outcomes in clinical trials

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