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However, more evidence is needed to clarify their systemic effects and controversial direct hepatic benefits
Who Should Think Twice: Athletes expecting a magic bullet for fat burning or dramatic performance gains
Both 25-hydroxylases (CYP2R1 and CYP27A1) were expressed in the liver, while CYP27A1 expression was seen only in cultured hepatocytes (FL83B mouse hepatocyte cell line)
I think this highlights the fact that these drugs need to be used the way they were intended, not for a short stint, and with appropriate support from providers. Side effects are really variable
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