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Besides, in H9c2 cardiomyocytes, GLP-1RAs also inhibit hypoxia-induced NLRP3 inflammasome activity and TNF- to attenuate pyroptosis through modulating the SIRT1/NADPH oxidase 4 (NOX4)/ROS pathway [139]
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If you have an autoimmune condition and are exploring GLP-1 therapy, sharing your Precision Peptide Genetic Test results with your rheumatologist or autoimmune physician can support a more nuanced conversation about whether GLP-1 fits your personalized treatment plan and what monitoring would be appropriate
Sana Umar is an Assistant Professor at Doon Medical College and Medical Reviewer at Karespot
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