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Description

Early work characterized stability in human gastric juice and resistance to enzymatic degradation under acidic conditions (Sikiric et al., 2011)

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GLP-1 RAs are not contraindicated in patients with prior atrial fibrillation, although the modest heart rate increase warrants monitoring

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MP0250 is a tri-specific DARPin drug that contains one hepatocyte growth factor (HGF)-binding DARPin, one vascular endothelial growth factor (VEGF)-binding DARPin, and two HSA-binding DARPins to extend its half-life 34

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