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doi: 10.7717/peerj.9753 278 MariIContrepoisKMoufarrejMNStelzerIAFeyaertsDHanXet al

But the greatest reduction in skin health is observed when women turn 50 years and experience menopause, which has a dramatic negative impact on skin aging owing to the loss of estrogen production from the ovaries, specifically the most potent estrogen in the body, which is 17-estradiol [2, 10, 14, 15]

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