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Several mechanisms are thought to contribute, and these should be understood as hypotheses based on the drug's pharmacology and observations from related incretin-based therapies: Reduced caloric intake: Retatrutide significantly suppresses appetite, often leading to a substantial reduction in food consumption
Improved Detoxification : Enhanced support for liver health and toxin elimination
Re-analysis of completers: A re-analysis of the same study data that excluded participants who discontinued treatment showed somewhat more encouraging results: 87.5% of those who received alpha-lipoic acid (versus 59.1% of placebo recipients) experienced a modest reduction in hepatic steatosis, and this difference was statistically significant
Immunohistochemistry was performed, as previously described (9, 24, 110)
