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The ferroptosis activator RSL-3 and the PI3K/Akt pathway inhibitor LY294002 reversed Neuritins inhibitory effect on ferroptosis, indicating that Neuritin suppresses neuronal ferroptosis via PI3K/Akt pathway activation (Song et al., 2025)
Interestingly, Lavi and colleagues 40 , through a mathematical model, showed how cancer cell density and cells alteration rate impact the heterogeneity over time, and its consequences on multidrug resistance
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