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The first is the oxidative phase in which glucose-6-phosphate is converted to ribulose-5-phosphate
In the STEP 1 trial, once-weekly 2.4mg semaglutide produced a mean 14.9% body-weight reduction over 68 weeks establishing GLP-1 agonism as a leading anti-obesity mechanism
The treatment may require multiple sessions depending on the desired outcome and the individuals response to the procedure
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