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The logic is strong
YM-254890 (Gq/11 protein inhibitor) can selectively inhibit IP1 production in a dose-dependent manner, and then block PLC-4 and downstream PKC/MAPK pathway, which inhibits the proliferation of UM cells ( The non-classical Wnt pathway composed of Wnt5a-PLC-4-Ca 2+ can reduce the proliferation and migration activity of CSCC cells, and inhibit the tumorigenicity of nude mice
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According to the Alzheimers Society, obesity from 35 to 65 years of age can raise the risk of dementia by up to 30%
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