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Identification and characterization of peptide drugs in unknown pharmaceutical preparations seized by the Belgian authorities: case report on AOD9604
[1] [2] For patients with documented hypersensitivity to other GLP-1 receptor agonists (such as semaglutide, dulaglutide, or liraglutide), cross-reactivity is uncertain due to differences in molecular structure
Hirayama T, Suzuki T
The binding modes of the clinically most widely used DPP-4 inhibitors have been characterized and based on these findings, three different classes of DPP-4 inhibitors have been proposed: Class 1 comprises of saxagliptin and vildagliptin, interacting with the S1- and S2 subsites of the active center and covalently binding with Ser630 of the DPP-4 molecule
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