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In oxidative stress models, cells treated with GHK-Cu show 65% reduction in malondialdehyde levels (a lipid peroxidation marker) and 80% increase in total antioxidant capacity compared to controls

Moreover, the types of fracture were divided into intertrochanteric fractures and femoral neck fractures instead of more strict classification such as OTA/AO classification

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An MJFF-funded Phase IIb placebo-controlled trial did show mild benefit but because the placebo group also improved, the significance of these results is unclear