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Brainstem atrophy and accompanying degeneration of the inferior olive is a recognized feature of WS 1,4,16,17
These are used as treatment options for type 2 diabetes by helping to control blood sugar levels
This is relevant because metabolic dysfunction-associated steatotic liver disease (MASLD, formerly NAFLD) is extremely common in people with obesity and is difficult to treat with conventional approaches
Accumulating evidence suggests that the gut microbiota may influence muscle function partly through SCFA-mediated mechanisms 53
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