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Based on the above results and our previous findings that inhibiting the cGAS-STING signaling pathway could suppress ferroptosis in skeletal stem cells derived from costal cartilage tissue [34], we hypothesized that GLP-1RAs might inhibit ferroptosis of chondrocytes by suppressing the activation of the cGAS-STING signaling pathway, and promote the synthesis of glycosaminoglycans and chondroitin sulfate, thereby alleviating the development of RA
Weight loss rates do slow over time, but this reflects a natural plateau as you approach a lower body weight rather than the medication becoming less effective
If well tolerated with no concerns, consider either maintaining 0.1 mg once daily or increasing to 0.125 mg once daily based on response
Mild swelling at injection site A small bump or slight puffiness where you injected is normalit's just the fluid sitting under the skin before absorption
